EcoDrugPlus


Synonyms	Bolvidon Mianserin hcl Mianserin hydrochloride NSC-759590 Norval ORG GB 94 ORG-GB 94 Tetramide
Status
Molecule Category	Salt-form
UNII	2X03TN217S

Synonyms

Bolvidon

Mianserin hcl

Mianserin hydrochloride

NSC-759590

Norval

ORG GB 94

ORG-GB 94

Tetramide

Status

Molecule Category

Salt-form

UNII

2X03TN217S


InChI Key	YNPFMWCWRVTGKJ-UHFFFAOYSA-N
Smiles	CN1CCN2c3ccccc3Cc3ccccc3C2C1.Cl
InChI	InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

InChI Key

YNPFMWCWRVTGKJ-UHFFFAOYSA-N

Smiles

CN1CCN2c3ccccc3Cc3ccccc3C2C1.Cl

InChI

InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

Property Name	Value
Molecular Formula	C18H21ClN2
Molecular Weight	300.83
AlogP	3.08
Hydrogen Bond Acceptor	2.0
Polar Surface Area	6.48
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	20.0

Property Name

Value

Molecular Formula

C18H21ClN2

Molecular Weight

300.83

AlogP

3.08

Hydrogen Bond Acceptor

2.0

Polar Surface Area

6.48

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

20.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor	-	6-300	-	-	-

Targets

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor

6-300

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	-	190	-	-	-

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Cavia porcellus

190

Resources	Reference
ChEBI	31843
ChEMBL	CHEMBL544428
FDA SRS	2X03TN217S
PubChem	68551
SureChEMBL	SCHEMBL340474

Resources

Reference

ChEBI

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

MIANSERIN HYDROCHLORIDE

Structure

Physicochemical Descriptors

Pharmacology

Cross References