AZD-0424


Synonyms	AZD0424 Azd-0424
Status
Molecule Category	Free-form
UNII	642PS51324

Pharmacology

Mechanism of Action	Action	Reference
Tyrosine-protein kinase ABL inhibitor	INHIBITOR	ClinicalTrials PubMed

Target Conservation


Protein: Tyrosine-protein kinase ABL Description: Tyrosine-protein kinase ABL1 Organism : Homo sapiens P00519 ENSG00000097007












Protein: Tyrosine-protein kinase SRC Description: Proto-oncogene tyrosine-protein kinase Src Organism : Homo sapiens P12931 ENSG00000197122

Cross References

Resources	Reference
ChEMBL	CHEMBL3545177
FDA SRS	642PS51324
PubChem	9893171

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025