EcoDrugPlus


Synonyms	Dianabol Metandienone Methandienone Methandrostenolone NSC-42722 Nerobol Perbolin
Status
Molecule Category	Free-form
UNII	COZ1R7EOCC
EPA CompTox	DTXSID2023276

Datasets:

Active Pharmaceutical Ingredients

Bioactive chemicals

Agrochemicals

Human Metabolites

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SubStructure

Threshold (%) >= 70


InChI Key	XWALNWXLMVGSFR-HLXURNFRSA-N
Smiles	C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(C)O
InChI	InChI=1S/C20H28O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h6,9,12,15-17,22H,4-5,7-8,10-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C20H28O2
Molecular Weight	300.44
AlogP	4.05
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Polar Surface Area	37.3
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	22.0

Mechanism of Action	Action	Reference
Androgen Receptor agonist	AGONIST	ISBN PubMed PubMed PubMed

Target Conservation


Protein: Androgen Receptor Description: Androgen receptor Organism : Homo sapiens P10275 ENSG00000169083

Cross References

Resources	Reference
ChEBI	6810
ChEMBL	CHEMBL1418176
DrugBank	DB13586
DrugCentral	1734
FDA SRS	COZ1R7EOCC
Human Metabolome Database	HMDB0041925
PubChem	6300
SureChEMBL	SCHEMBL140928
ZINC	ZINC000003875469

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

METHANDROSTENOLONE

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References