| Synonyms | |
| Status | |
| Molecule Category | UNKNOWN |
| UNII | 7X6P5N8K2L |
| EPA CompTox | DTXSID90175413 |
Structure
| InChI Key | XFVRBYKKGGDPAJ-UHFFFAOYSA-N |
|---|---|
| Smiles | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C12H13N3O2 |
| Molecular Weight | 231.25 |
| AlogP | 1.85 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 59.23 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 17.0 |
Bioactivity
| Mechanism of Action | Action | Reference |
|---|---|---|
| Glutamate receptor ionotropic AMPA positive allosteric modulator | POSITIVE ALLOSTERIC MODULATOR | PubMed Wikipedia |
|
Protein: Glutamate receptor ionotropic AMPA Description: Glutamate receptor 1 Organism : Homo sapiens P42261 ENSG00000155511 |
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Protein: Glutamate receptor ionotropic AMPA Description: Glutamate receptor 2 Organism : Homo sapiens P42262 ENSG00000120251 |
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Protein: Glutamate receptor ionotropic AMPA Description: Glutamate receptor 3 Organism : Homo sapiens P42263 ENSG00000125675 |
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Protein: Glutamate receptor ionotropic AMPA Description: Glutamate receptor 4 Organism : Homo sapiens P48058 ENSG00000152578 |
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| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Ligand-gated ion channel
Ionotropic glutamate receptor
AMPA receptor
|
14000 | - | - | - | - |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL1276138 |
| DrugBank | DB15012 |
| FDA SRS | 7X6P5N8K2L |
| PubChem | 4118151 |
| SureChEMBL | SCHEMBL677135 |
| ZINC | ZINC000000007461 |
CONTENTS