EcoDrugPlus


Synonyms	Azimilide
Status
Molecule Category	Free-form
UNII	74QU6P2934


InChI Key	MREBEPTUUMTTIA-PCLIKHOPSA-N
Smiles	CN1CCN(CCCCN2C(=O)CN(/N=C/c3ccc(-c4ccc(Cl)cc4)o3)C2=O)CC1
InChI	InChI=1S/C23H28ClN5O3/c1-26-12-14-27(15-13-26)10-2-3-11-28-22(30)17-29(23(28)31)25-16-20-8-9-21(32-20)18-4-6-19(24)7-5-18/h4-9,16H,2-3,10-15,17H2,1H3/b25-16+

Property Name	Value
Molecular Formula	C23H28ClN5O3
Molecular Weight	457.96
AlogP	3.23
Hydrogen Bond Acceptor	6.0
Number of Rotational Bond	8.0
Polar Surface Area	72.6
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	32.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel	-	180-562.34	-	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	-	180-240	-	-	-
Homo sapiens	-	562.34-562.34	-	-	-

Resources	Reference
ChEBI	34545
ChEMBL	CHEMBL123558
FDA SRS	74QU6P2934
Guide to Pharmacology	2588
KEGG	C13777
PubChem	60939
SureChEMBL	SCHEMBL26354
ZINC	ZINC000021983255

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

AZIMILIDE

Structure

Physicochemical Descriptors

Pharmacology

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