EcoDrugPlus


Synonyms	Di-methox Sodium sulfadimethoxine Sulfadimethoxine sodium Sulfadimethoxine sodium salt
Status
Molecule Category	Salt-form
UNII	49DG2B481W
EPA CompTox	DTXSID50858735

Synonyms

Di-methox

Sodium sulfadimethoxine

Sulfadimethoxine sodium

Sulfadimethoxine sodium salt

Status

Molecule Category

Salt-form

UNII

49DG2B481W

EPA CompTox

DTXSID50858735


InChI Key	DQDZQHMCPDUUPC-UHFFFAOYSA-N
Smiles	COc1cc([N-]S(=O)(=O)c2ccc(N)cc2)nc(OC)n1.[Na+]
InChI	InChI=1S/C12H13N4O4S.Na/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9;/h3-7H,13H2,1-2H3;/q-1;+1

InChI Key

DQDZQHMCPDUUPC-UHFFFAOYSA-N

Smiles

COc1cc([N-]S(=O)(=O)c2ccc(N)cc2)nc(OC)n1.[Na+]

InChI

InChI=1S/C12H13N4O4S.Na/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9;/h3-7H,13H2,1-2H3;/q-1;+1

Property Name	Value
Molecular Formula	C12H13N4NaO4S
Molecular Weight	332.32
AlogP	0.88
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	5.0
Polar Surface Area	116.43
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	21.0

Property Name

Value

Molecular Formula

C12H13N4NaO4S

Molecular Weight

332.32

AlogP

0.88

Hydrogen Bond Acceptor

7.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

5.0

Polar Surface Area

116.43

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

21.0

Mechanism of Action	Action	Reference
Bacterial dihydropteroate synthase inhibitor	INHIBITOR	PubMed PubMed Wikipedia

Mechanism of Action

Action

Reference

Bacterial dihydropteroate synthase inhibitor

INHIBITOR

PubMed PubMed Wikipedia

Resources	Reference
ChEBI	81722
ChEMBL	CHEMBL2107253
FDA SRS	49DG2B481W
KEGG	C18386
PubChem	13384041

Resources

Reference

ChEBI

ChEMBL

FDA SRS

KEGG

PubChem

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

SULFADIMETHOXINE SODIUM

Structure

Physicochemical Descriptors

Pharmacology

Cross References