EcoDrugPlus


Synonyms	Amplivix Benziodarone L 2329 L-2329 NSC-82133
Status
Molecule Category	Free-form
ATC	C01DX04
UNII	75CL65GTYR
EPA CompTox	DTXSID1046134


InChI Key	CZCHIEJNWPNBDE-UHFFFAOYSA-N
Smiles	CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1
InChI	InChI=1S/C17H12I2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3

Property Name	Value
Molecular Formula	C17H12I2O3
Molecular Weight	518.09
AlogP	5.14
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	3.0
Polar Surface Area	50.44
Molecular species	ACID
Aromatic Rings	3.0
Heavy Atoms	22.0

Mechanism of Action	Action	Reference
Calmodulin inhibitor	INHIBITOR	PubMed PubMed PubMed PubMed PubMed PubMed

Resources	Reference
ChEBI	135814
ChEMBL	CHEMBL232201
DrugBank	DB13277
DrugCentral	321
FDA SRS	75CL65GTYR
PubChem	6237
SureChEMBL	SCHEMBL308541
ZINC	ZINC000003875456

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

BENZIODARONE

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Cross References