EcoDrugPlus


Synonyms	Delapril
Status
Molecule Category	Free-form
ATC	C09AA12
UNII	W77UAL9THI


InChI Key	WOUOLAUOZXOLJQ-MBSDFSHPSA-N
Smiles	CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N(CC(=O)O)C1Cc2ccccc2C1
InChI	InChI=1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1

Property Name	Value
Molecular Formula	C26H32N2O5
Molecular Weight	452.55
AlogP	2.61
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	11.0
Polar Surface Area	95.94
Molecular species	ACID
Aromatic Rings	2.0
Heavy Atoms	33.0

Mechanism of Action	Action	Reference
Angiotensin-converting enzyme inhibitor	INHIBITOR	PubMed

Resources	Reference
ChEBI	135735
ChEMBL	CHEMBL589583
DrugBank	DB13312
DrugCentral	798
FDA SRS	W77UAL9THI
PubChem	5362116
SureChEMBL	SCHEMBL34120
ZINC	ZINC000003794599

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

DELAPRIL

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References


Protein: Angiotensin-converting enzyme Description: Angiotensin-converting enzyme Organism : Homo sapiens P12821 ENSG00000159640