DE-104


Synonyms	De-104
Status
Molecule Category	Free-form

Pharmacology

Mechanism of Action	Action	Reference
Rho-associated protein kinase inhibitor	INHIBITOR	PubMed

Target Conservation


Protein: Rho-associated protein kinase Description: Rho-associated protein kinase 2 Organism : Homo sapiens O75116 ENSG00000134318












Protein: Rho-associated protein kinase Description: Rho-associated protein kinase 1 Organism : Homo sapiens Q13464 ENSG00000067900

Cross References

Resources	Reference
ChEMBL	CHEMBL3545153

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025