GSK-2256098

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Synonyms
Status
Molecule Category Free-form
UNII R7O0O4110G

Structure

InChI Key BVAHPPKGOOJSPU-UHFFFAOYSA-N
Smiles CONC(=O)c1ccccc1Nc1cc(Nc2cc(C)nn2C(C)C)ncc1Cl
InChI
InChI=1S/C20H23ClN6O2/c1-12(2)27-19(9-13(3)25-27)24-18-10-17(15(21)11-22-18)23-16-8-6-5-7-14(16)20(28)26-29-4/h5-12H,1-4H3,(H,26,28)(H2,22,23,24)

Pharmacology

Mechanism of Action Action Reference
Focal adhesion kinase 1 inhibitor INHIBITOR PubMed DOI
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Kinase Protein Kinase TK protein kinase group Tyrosine protein kinase Fak family
- 0.4-15 - - -
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
- 0.4-15 - - -

Target Conservation

Protein: Focal adhesion kinase 1
Description: Focal adhesion kinase 1
Organism : Homo sapiens
Q05397 ENSG00000169398

Cross References

Resources Reference
ChEMBL CHEMBL3544967
FDA SRS R7O0O4110G
PubChem 46214930
CONTENTS