EcoDrugPlus


Synonyms	Acupan NSC-757856 Nefopam hcl Nefopam hydrochloride
Status
Molecule Category	Salt-form
UNII	685J48E13W
EPA CompTox	DTXSID7045441

Synonyms

Acupan

NSC-757856

Nefopam hcl

Nefopam hydrochloride

Status

Molecule Category

Salt-form

UNII

685J48E13W

EPA CompTox

DTXSID7045441


InChI Key	CNNVSINJDJNHQK-UHFFFAOYSA-N
Smiles	CN1CCOC(c2ccccc2)c2ccccc2C1.Cl
InChI	InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H

InChI Key

CNNVSINJDJNHQK-UHFFFAOYSA-N

Smiles

CN1CCOC(c2ccccc2)c2ccccc2C1.Cl

InChI

InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H

Property Name	Value
Molecular Formula	C17H20ClNO
Molecular Weight	289.81
AlogP	3.24
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	1.0
Polar Surface Area	12.47
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	19.0

Property Name

Value

Molecular Formula

C17H20ClNO

Molecular Weight

289.81

AlogP

3.24

Hydrogen Bond Acceptor

2.0

Number of Rotational Bond

1.0

Polar Surface Area

12.47

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

19.0

Resources	Reference
ChEMBL	CHEMBL1407915
FDA SRS	685J48E13W
PubChem	31872
SureChEMBL	SCHEMBL122057

Resources

Reference

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

NEFOPAM HYDROCHLORIDE

Structure

Physicochemical Descriptors

Cross References