EcoDrugPlus


Synonyms	Gppe susp fte Guanimycin NSC-14041 Sulfaguanidine Sulphaguanidine
Status
Molecule Category	Free-form
ATC	A07AB03
UNII	15XQ8043FN
EPA CompTox	DTXSID1023609


InChI Key	BRBKOPJOKNSWSG-UHFFFAOYSA-N
Smiles	N=C(N)NS(=O)(=O)c1ccc(N)cc1
InChI	InChI=1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)

Property Name	Value
Molecular Formula	C7H10N4O2S
Molecular Weight	214.25
AlogP	-0.77
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	2.0
Polar Surface Area	124.56
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	14.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Protease Serine protease Serine protease PA clan Serine protease S1A subfamily	-	-	-	95	-
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	107.96-119.19

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	107.96-119.19

Resources	Reference
ChEBI	94621
ChEMBL	CHEMBL338802
DrugBank	DB13726
DrugCentral	2505
FDA SRS	15XQ8043FN
PubChem	5324
SureChEMBL	SCHEMBL93639
ZINC	ZINC000003873927

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

SULFAGUANIDINE

Structure

Physicochemical Descriptors

Pharmacology

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