EcoDrugPlus


Synonyms	Dex-m74 Mannac N-acetylmannosamine
Status
Molecule Category	Free-form
UNII	X80PR7P73R
EPA CompTox	DTXSID001350111


InChI Key	OVRNDRQMDRJTHS-UOLFYFMNSA-N
Smiles	CC(=O)N[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O
InChI	InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5+,6-,7-,8+/m1/s1

Property Name	Value
Molecular Formula	C8H15NO6
Molecular Weight	221.21
AlogP	-3.08
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	5.0
Number of Rotational Bond	2.0
Polar Surface Area	119.25
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	15.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor	-	199.53	-	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Rattus norvegicus	-	199.53	-	-	-

Resources	Reference
CAS NUMBER	3615-17-6
ChEBI	41112
ChEMBL	CHEMBL1231391
FDA SRS	X80PR7P73R
PDB	BM3
PubChem	65150
SureChEMBL	SCHEMBL379737
ZINC	ZINC000004096030

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, Volume 54, Issue D1, 6 January 2026, Pages D1397–D1404, https://doi.org/10.1093/nar/gkaf1251

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 23^rd March 2026

N-ACETYLMANNOSAMINE

Structure

Physicochemical Descriptors

Pharmacology

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