LY-3200882

/static/temp/default.svg Search structure
Synonyms
Status
Molecule Category Free-form
UNII 19HY34R6UN

Structure

InChI Key PNPFMWIDAKQFPY-UHFFFAOYSA-N
Smiles CC(C)(O)c1cc(Nc2cc(Oc3cn(C4CC4)nc3C3CCOCC3)ccn2)ccn1
InChI
InChI=1S/C24H29N5O3/c1-24(2,30)21-13-17(5-9-25-21)27-22-14-19(6-10-26-22)32-20-15-29(18-3-4-18)28-23(20)16-7-11-31-12-8-16/h5-6,9-10,13-16,18,30H,3-4,7-8,11-12H2,1-2H3,(H,25,26,27)

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H29N5O3
Molecular Weight 435.53
AlogP 4.67
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 7.0
Polar Surface Area 94.32
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 32.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Kinase Protein Kinase TKL protein kinase group TKL protein kinase STKR family TKL protein kinase STKR Type 1 subfamily
- 38.2-82.9 - - -
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
- 38.2 - - -
Mus musculus
- 82.9 - - -

Cross References

Resources Reference
ChEMBL CHEMBL4594432
FDA SRS 19HY34R6UN
PubChem 121249291
SureChEMBL SCHEMBL17645407
CONTENTS