AZD-8848

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Synonyms
Status
Molecule Category Free-form
UNII 322ZMR6920

Structure

InChI Key FEFIBEHSXLKJGI-UHFFFAOYSA-N
Smiles CCCCOc1nc(N)c2[nH]c(=O)n(CCCN(CCCN3CCOCC3)Cc3cccc(CC(=O)OC)c3)c2n1
InChI
InChI=1S/C29H43N7O5/c1-3-4-16-41-28-32-26(30)25-27(33-28)36(29(38)31-25)13-7-12-35(11-6-10-34-14-17-40-18-15-34)21-23-9-5-8-22(19-23)20-24(37)39-2/h5,8-9,19H,3-4,6-7,10-18,20-21H2,1-2H3,(H,31,38)(H2,30,32,33)

Physicochemical Descriptors

Property Name Value
Molecular Formula C29H43N7O5
Molecular Weight 569.71
AlogP 2.21
Hydrogen Bond Acceptor 11.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 16.0
Polar Surface Area 140.83
Molecular species BASE
Aromatic Rings 3.0
Heavy Atoms 41.0

Pharmacology

Mechanism of Action Action Reference
Toll-like receptor 7 agonist AGONIST PubMed PubMed

Target Conservation

Protein: Toll-like receptor 7
Description: Toll-like receptor 7
Organism : Homo sapiens
Q9NYK1 ENSG00000196664

Related Entries

Cross References

Resources Reference
ChEMBL CHEMBL4297356
DrugBank DB14868
FDA SRS 322ZMR6920
Guide to Pharmacology 9256
PubChem 11592228
SureChEMBL SCHEMBL12047493
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