EcoDrugPlus


Synonyms	DTI-0009 GR-56072 GR56072 RG-14202 Selodenoson
Status
Molecule Category	Free-form
UNII	103G5E953K
EPA CompTox	DTXSID00149201

Datasets:

Active Pharmaceutical Ingredients

Bioactive chemicals

Agrochemicals

Human Metabolites

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SubStructure

Threshold (%) >= 70


InChI Key	GWVQGVCXFNYGFP-PFHKOEEOSA-N
Smiles	CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)ncnc32)[C@H](O)[C@@H]1O
InChI	InChI=1S/C17H24N6O4/c1-2-18-16(26)13-11(24)12(25)17(27-13)23-8-21-10-14(19-7-20-15(10)23)22-9-5-3-4-6-9/h7-9,11-13,17,24-25H,2-6H2,1H3,(H,18,26)(H,19,20,22)/t11-,12+,13-,17+/m0/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C17H24N6O4
Molecular Weight	376.42
AlogP	-0.06
Hydrogen Bond Acceptor	9.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	5.0
Polar Surface Area	134.42
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	27.0

Mechanism of Action	Action	Reference
Adenosine A1 receptor agonist	AGONIST	PubMed

Target Conservation


Protein: Adenosine A1 receptor Description: Adenosine receptor A1 Organism : Homo sapiens P30542 ENSG00000163485

Cross References

Resources	Reference
ChEMBL	CHEMBL2107371
DrugBank	DB16325
FDA SRS	103G5E953K
PubChem	3082555
SureChEMBL	SCHEMBL2544415

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

SELODENOSON

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References