EcoDrugPlus


Synonyms	ASP-2151 ASP2151 Amenamevir Asp2151
Status
Molecule Category	Free-form
ATC	J05AX26
UNII	94X46KW4AE

Synonyms

ASP-2151

ASP2151

Amenamevir

Asp2151

Status

Molecule Category

Free-form

ATC

J05AX26

UNII

94X46KW4AE


InChI Key	MNHNIVNAFBSLLX-UHFFFAOYSA-N
Smiles	Cc1cccc(C)c1N(CC(=O)Nc1ccc(-c2ncon2)cc1)C(=O)C1CCS(=O)(=O)CC1
InChI	InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)

InChI Key

MNHNIVNAFBSLLX-UHFFFAOYSA-N

Smiles

Cc1cccc(C)c1N(CC(=O)Nc1ccc(-c2ncon2)cc1)C(=O)C1CCS(=O)(=O)CC1

InChI

InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)

Property Name	Value
Molecular Formula	C24H26N4O5S
Molecular Weight	482.56
AlogP	3.15
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	6.0
Polar Surface Area	122.47
Molecular species	NEUTRAL
Aromatic Rings	3.0
Heavy Atoms	34.0

Property Name

Value

Molecular Formula

C24H26N4O5S

Molecular Weight

482.56

AlogP

3.15

Hydrogen Bond Acceptor

7.0

Hydrogen Bond Donor

1.0

Number of Rotational Bond

6.0

Polar Surface Area

122.47

Molecular species

NEUTRAL

Aromatic Rings

3.0

Heavy Atoms

34.0

Mechanism of Action	Action	Reference
Helicase primate complex inhibitor	INHIBITOR	PMDA PubMed

Mechanism of Action

Action

Reference

Helicase primate complex inhibitor

INHIBITOR

PMDA PubMed

Resources	Reference
ChEMBL	CHEMBL4297592
DrugBank	DB11701
DrugCentral	5266
FDA SRS	94X46KW4AE
PubChem	11397521
SureChEMBL	SCHEMBL2238614

Resources

Reference

ChEMBL

DrugBank

DrugCentral

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

AMENAMEVIR

Structure

Physicochemical Descriptors

Pharmacology

Cross References