EcoDrugPlus


Synonyms	PZ-601 Razupenem SM-216601 SMP-601
Status
Molecule Category	Free-form
UNII	26020H3Q1L

Synonyms

PZ-601

Razupenem

SM-216601

SMP-601

Status

Molecule Category

Free-form

UNII

26020H3Q1L


InChI Key	XFGOMLIRJYURLQ-GOKYHWASSA-N
Smiles	C[C@H]1C=C(c2csc(SC3=C(C(=O)O)N4C(=O)[C@H]([C@@H](C)O)[C@H]4[C@H]3C)n2)CN1
InChI	InChI=1S/C18H21N3O4S2/c1-7-4-10(5-19-7)11-6-26-18(20-11)27-15-8(2)13-12(9(3)22)16(23)21(13)14(15)17(24)25/h4,6-9,12-13,19,22H,5H2,1-3H3,(H,24,25)/t7-,8+,9+,12+,13+/m0/s1

InChI Key

XFGOMLIRJYURLQ-GOKYHWASSA-N

Smiles

C[C@H]1C=C(c2csc(SC3=C(C(=O)O)N4C(=O)[C@H]([C@@H](C)O)[C@H]4[C@H]3C)n2)CN1

InChI

InChI=1S/C18H21N3O4S2/c1-7-4-10(5-19-7)11-6-26-18(20-11)27-15-8(2)13-12(9(3)22)16(23)21(13)14(15)17(24)25/h4,6-9,12-13,19,22H,5H2,1-3H3,(H,24,25)/t7-,8+,9+,12+,13+/m0/s1

Property Name	Value
Molecular Formula	C18H21N3O4S2
Molecular Weight	407.52
AlogP	1.76
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	5.0
Polar Surface Area	102.76
Molecular species	ZWITTERION
Aromatic Rings	1.0
Heavy Atoms	27.0

Property Name

Value

Molecular Formula

C18H21N3O4S2

Molecular Weight

407.52

AlogP

1.76

Hydrogen Bond Acceptor

7.0

Hydrogen Bond Donor

3.0

Number of Rotational Bond

5.0

Polar Surface Area

102.76

Molecular species

ZWITTERION

Aromatic Rings

1.0

Heavy Atoms

27.0

Mechanism of Action	Action	Reference
Bacterial penicillin-binding protein inhibitor	INHIBITOR	PubMed PubMed PubMed

Mechanism of Action

Action

Reference

Bacterial penicillin-binding protein inhibitor

INHIBITOR

PubMed PubMed PubMed

Resources	Reference
ChEMBL	CHEMBL1256722
DrugBank	DB12587
FDA SRS	26020H3Q1L
Guide to Pharmacology	10851
PubChem	10993211
SureChEMBL	SCHEMBL2894324
ZINC	ZINC000003986713

Resources

Reference

ChEMBL

CHEMBL1256722

DrugBank

DB12587

FDA SRS

26020H3Q1L

Guide to Pharmacology

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

RAZUPENEM

Structure

Physicochemical Descriptors

Pharmacology

Cross References