EcoDrugPlus


Synonyms	Amlodipine, (s)- Levamlodipine S-amlodipine
Status
Molecule Category	Free-form
UNII	0P6NLP6806


InChI Key	HTIQEAQVCYTUBX-KRWDZBQOSA-N
Smiles	CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)[C@@H]1c1ccccc1Cl
InChI	InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m0/s1

Property Name	Value
Molecular Formula	C20H25ClN2O5
Molecular Weight	408.88
AlogP	2.27
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	8.0
Polar Surface Area	99.88
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	28.0

Resources	Reference
ChEBI	53796
ChEMBL	CHEMBL2111097
DrugBank	DB09237
DrugCentral	4099
FDA SRS	0P6NLP6806
PDB	6UB
PubChem	9822750
SureChEMBL	SCHEMBL41283
ZINC	ZINC000100001964

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

LEVAMLODIPINE

Structure

Physicochemical Descriptors

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