REMOXIPRIDE HYDROCHLORIDE

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Search structure


Synonyms	(-)-FLA-731 A 33547.HCL.H20 FLA 731(-) FLA-731 Remoxipride hcl Remoxipride hydrochloride Roxiam Roxiam ir
Status
Molecule Category	Salt-form
UNII	MH4OU8RWCW
EPA CompTox	DTXSID00151829

Structure


InChI Key	SPFVHFBNXPARTR-IDMXKUIJSA-N
Smiles	CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC.Cl.O
InChI	InChI=1S/C16H23BrN2O3.ClH.H2O/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3;;/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20);1H;1H2/t11-;;/m0../s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C16H26BrClN2O4
Molecular Weight	425.75
AlogP	2.68
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	6.0
Polar Surface Area	50.8
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	22.0

Pharmacology

Mechanism of Action	Action	Reference
Dopamine D2 receptor antagonist	ANTAGONIST	PubMed PubMed PubMed PubMed PubMed

Target Conservation


Protein: Dopamine D2 receptor Description: D(2) dopamine receptor Organism : Homo sapiens P14416 ENSG00000149295

Cross References

Resources	Reference
ChEMBL	CHEMBL3989556
FDA SRS	MH4OU8RWCW
PubChem	60678
SureChEMBL	SCHEMBL122728

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025