RSV-604

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Synonyms
Status
Molecule Category Free-form
UNII 6NF9HI6D98

Structure

InChI Key MTPVBMVUENFFLL-HXUWFJFHSA-N
Smiles O=C(Nc1ccccc1F)N[C@H]1N=C(c2ccccc2)c2ccccc2NC1=O
InChI
InChI=1S/C22H17FN4O2/c23-16-11-5-7-13-18(16)25-22(29)27-20-21(28)24-17-12-6-4-10-15(17)19(26-20)14-8-2-1-3-9-14/h1-13,20H,(H,24,28)(H2,25,27,29)/t20-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H17FN4O2
Molecular Weight 388.4
AlogP 3.76
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 3.0
Polar Surface Area 82.59
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 29.0

Pharmacology

Mechanism of Action Action Reference
Nucleoprotein inhibitor INHIBITOR PubMed
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Bovine respiratory syncytial virus
300 - - - -
Respiratory syncytial virus
500-900 700-900 - - -

Cross References

Resources Reference
ChEMBL CHEMBL223402
DrugBank DB15197
FDA SRS 6NF9HI6D98
PubChem 5279172
SureChEMBL SCHEMBL641779
ZINC ZINC000003986763
CONTENTS