ELZASONAN HYDROCHLORIDE

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Search structure


Synonyms	CP-448,187-01 Cp-448187-01 Elzasonan hcl Elzasonan hydrochloride
Status
Molecule Category	Salt-form
UNII	X38F62RR8L

Structure


InChI Key	NMTRXBJYASHMND-UXTSPRGOSA-N
Smiles	CN1CCN(c2ccccc2/C=C2\SCCN(c3ccc(Cl)c(Cl)c3)C2=O)CC1.Cl
InChI	InChI=1S/C22H23Cl2N3OS.ClH/c1-25-8-10-26(11-9-25)20-5-3-2-4-16(20)14-21-22(28)27(12-13-29-21)17-6-7-18(23)19(24)15-17;/h2-7,14-15H,8-13H2,1H3;1H/b21-14-;

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C22H24Cl3N3OS
Molecular Weight	484.88
AlogP	4.87
Hydrogen Bond Acceptor	4.0
Number of Rotational Bond	3.0
Polar Surface Area	26.79
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	29.0

Pharmacology

Mechanism of Action	Action	Reference
Serotonin 1b (5-HT1b) receptor antagonist	ANTAGONIST	PubMed Wikipedia

Target Conservation


Protein: Serotonin 1d (5-HT1d) receptor Description: 5-hydroxytryptamine receptor 1D Organism : Homo sapiens P28221 ENSG00000179546








Protein: Serotonin 1b (5-HT1b) receptor Description: 5-hydroxytryptamine receptor 1B Organism : Homo sapiens P28222 ENSG00000135312

Cross References

Resources	Reference
ChEMBL	CHEMBL3989805
FDA SRS	X38F62RR8L
PubChem	6506051

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025