EcoDrugPlus


Synonyms	Carbinoxamine Clistin Palgic
Status
Molecule Category	Free-form
ATC	R06AA08
UNII	982A7M02H5
EPA CompTox	DTXSID4022737


InChI Key	OJFSXZCBGQGRNV-UHFFFAOYSA-N
Smiles	CN(C)CCOC(c1ccc(Cl)cc1)c1ccccn1
InChI	InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3

Property Name	Value
Molecular Formula	C16H19ClN2O
Molecular Weight	290.79
AlogP	3.4
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	6.0
Polar Surface Area	25.36
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	20.0

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	250	-	-	-	28-62

Resources	Reference
ChEBI	3398
ChEMBL	CHEMBL864
DrugBank	DB00748
DrugCentral	499
FDA SRS	982A7M02H5
Human Metabolome Database	HMDB0014886
Guide to Pharmacology	7139
KEGG	C06871
PharmGKB	PA164746898
PubChem	2564
SureChEMBL	SCHEMBL5070

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

CARBINOXAMINE

Structure

Physicochemical Descriptors

Pharmacology

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