EcoDrugPlus


Synonyms	KC-8857 KC8857 Tedisamil
Status
Molecule Category	Free-form
ATC	C01BD06
UNII	A5VAY2U3R8


InChI Key	CTIRHWCPXYGDGF-HDICACEKSA-N
Smiles	C1CCC2(C1)[C@H]1CN(CC3CC3)C[C@@H]2CN(CC2CC2)C1
InChI	InChI=1S/C19H32N2/c1-2-8-19(7-1)17-11-20(9-15-3-4-15)12-18(19)14-21(13-17)10-16-5-6-16/h15-18H,1-14H2/t17-,18+

Property Name	Value
Molecular Formula	C19H32N2
Molecular Weight	288.48
AlogP	3.23
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	4.0
Polar Surface Area	6.48
Molecular species	BASE
Aromatic Rings	0.0
Heavy Atoms	21.0

Mechanism of Action	Action	Reference
Voltage-gated potassium channel blocker	BLOCKER	PubMed PubMed

Resources	Reference
ChEBI	134747
ChEMBL	CHEMBL2111110
DrugCentral	4655
FDA SRS	A5VAY2U3R8
PubChem	65825
SureChEMBL	SCHEMBL10025758

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TEDISAMIL

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Cross References