EcoDrugPlus


Synonyms	Flutemetamol [3H]-Flutemetamol
Status
Molecule Category	Free-form
UNII	0F3M7032P5


InChI Key	VVECGOCJFKTUAX-UHFFFAOYSA-N
Smiles	CNc1ccc(-c2nc3ccc(O)cc3s2)cc1F
InChI	InChI=1S/C14H11FN2OS/c1-16-11-4-2-8(6-10(11)15)14-17-12-5-3-9(18)7-13(12)19-14/h2-7,16,18H,1H3

Property Name	Value
Molecular Formula	C14H11FN2OS
Molecular Weight	274.32
AlogP	3.85
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	2.0
Polar Surface Area	45.15
Molecular species	NEUTRAL
Aromatic Rings	3.0
Heavy Atoms	19.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor	-	24	-	0.74	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	24	-	0.74	-

Resources	Reference
ChEMBL	CHEMBL579205
DrugBank	DB15058
FDA SRS	0F3M7032P5
PubChem	10107393
SureChEMBL	SCHEMBL10032130
ZINC	ZINC000034220093

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

FLUTEMETAMOL

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

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