PILOCARPINE NITRATE

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Synonyms
Status
Molecule Category Salt-form
UNII M20T465H6J
EPA CompTox DTXSID80883277

Structure

InChI Key PRZXEPJJHQYOGF-GNAZCLTHSA-N
Smiles CC[C@@H]1C(=O)OC[C@@H]1Cc1cncn1C.O=[N+]([O-])O
InChI
InChI=1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C11H17N3O5
Molecular Weight 271.27
AlogP 1.16
Hydrogen Bond Acceptor 4.0
Number of Rotational Bond 3.0
Polar Surface Area 44.12
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 15.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 82.84-95.87
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Cricetulus griseus
- - - - 82.84-95.87

Cross References

Resources Reference
ChEMBL CHEMBL1213136
FDA SRS M20T465H6J
PubChem 657349
SureChEMBL SCHEMBL41889
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