MINOPAFANT

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Synonyms
Status
Molecule Category Free-form
UNII I7J5MAD9ZU

Structure

InChI Key HGOAIWZFTWACBD-RRHRGVEJSA-O
Smiles CCCCCCCCCCCCCCCCCCNC(=O)OC1CCN(C(=O)OC[C@H](COC(=O)N(Cc2cccc[n+]2CC)C(=O)c2ccccc2OC)OC)CC1
InChI
InChI=1S/C46H72N4O9/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-24-31-47-44(52)59-39-29-33-49(34-30-39)45(53)57-36-40(55-3)37-58-46(54)50(35-38-26-23-25-32-48(38)6-2)43(51)41-27-21-22-28-42(41)56-4/h21-23,25-28,32,39-40H,5-20,24,29-31,33-37H2,1-4H3/p+1/t40-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C46H73N4O9+
Molecular Weight 826.11
AlogP 9.39
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 28.0
Polar Surface Area 136.82
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 59.0

Pharmacology

Mechanism of Action Action Reference
Platelet activating factor receptor antagonist ANTAGONIST PubMed

Target Conservation

Protein: Platelet activating factor receptor
Description: Platelet-activating factor receptor
Organism : Homo sapiens
P25105 ENSG00000169403

Cross References

Resources Reference
ChEMBL CHEMBL2110618
FDA SRS I7J5MAD9ZU
PubChem 130990
ZINC ZINC000085536954
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