EcoDrugPlus


Synonyms	Butenafine Mentax Mentax-TC
Status
Molecule Category	Free-form
ATC	D01AE23
UNII	91Y494NL0X
EPA CompTox	DTXSID7040657

Synonyms

Butenafine

Mentax

Mentax-TC

Status

Molecule Category

Free-form

ATC

D01AE23

UNII

91Y494NL0X

EPA CompTox

DTXSID7040657


InChI Key	ABJKWBDEJIDSJZ-UHFFFAOYSA-N
Smiles	CN(Cc1ccc(C(C)(C)C)cc1)Cc1cccc2ccccc12
InChI	InChI=1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3

InChI Key

ABJKWBDEJIDSJZ-UHFFFAOYSA-N

Smiles

CN(Cc1ccc(C(C)(C)C)cc1)Cc1cccc2ccccc12

InChI

InChI=1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3

Property Name	Value
Molecular Formula	C23H27N
Molecular Weight	317.48
AlogP	5.77
Hydrogen Bond Acceptor	1.0
Number of Rotational Bond	4.0
Polar Surface Area	3.24
Molecular species	BASE
Aromatic Rings	3.0
Heavy Atoms	24.0

Property Name

Value

Molecular Formula

C23H27N

Molecular Weight

317.48

AlogP

5.77

Hydrogen Bond Acceptor

1.0

Number of Rotational Bond

4.0

Polar Surface Area

3.24

Molecular species

BASE

Aromatic Rings

3.0

Heavy Atoms

24.0

Resources	Reference
ChEBI	3238
ChEMBL	CHEMBL990
DrugBank	DB01091
DrugCentral	444
FDA SRS	91Y494NL0X
Human Metabolome Database	HMDB0015223
KEGG	C08067
PharmGKB	PA164745478
PubChem	2484
SureChEMBL	SCHEMBL65526
ZINC	ZINC000001530975

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Human Metabolome Database

KEGG

PharmGKB

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

BUTENAFINE

Structure

Physicochemical Descriptors

Cross References