DEXTROMORAMIDE


Synonyms	Acscn-9613 Alcoid Dextromoramide IDS-ND-003 Jetrium Linfadol MCP-875 Moramide Narcolo Palfadonna R-875 Racemoramide, (s)- SKF-5137 Troxilan Yetrium
Status
Molecule Category	Free-form
ATC	N02AC01
UNII	9S4S6CIY83

Structure


InChI Key	XHKXWINHANRSNT-NRFANRHFSA-N
Smiles	C[C@@H](CC(C(=O)N1CCCC1)(c1ccccc1)c1ccccc1)N1CCOCC1
InChI	InChI=1S/C25H32N2O2/c1-21(26-16-18-29-19-17-26)20-25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3/t21-/m0/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C25H32N2O2
Molecular Weight	392.54
AlogP	3.71
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	6.0
Polar Surface Area	32.78
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	29.0

Pharmacology

Mechanism of Action	Action	Reference
Opioid receptors; mu/kappa/delta agonist	AGONIST	PubMed PubMed

Target Conservation


Protein: Opioid receptors; mu/kappa/delta Description: Mu-type opioid receptor Organism : Homo sapiens P35372 ENSG00000112038












Protein: Opioid receptors; mu/kappa/delta Description: Delta-type opioid receptor Organism : Homo sapiens P41143 ENSG00000116329










Protein: Opioid receptors; mu/kappa/delta Description: Kappa-type opioid receptor Organism : Homo sapiens P41145 ENSG00000082556

Related Entries

Cross References

Resources	Reference
ChEMBL	CHEMBL3833389
FDA SRS	9S4S6CIY83
PubChem	92943

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025