EcoDrugPlus


Synonyms	L-084 LJC 11,084 LJC 11084 LJC-11084 ME-1211 ME1211 Orapenem TBPM-PI Tebipenem pivoxil
Status
Molecule Category	Free-form
ATC	J01DH06
UNII	95AK1A52I8
EPA CompTox	DTXSID00167228


InChI Key	SNUDIPVBUUXCDG-QHSBEEBCSA-N
Smiles	C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCOC(=O)C(C)(C)C)=C(SC3CN(C4=NCCS4)C3)[C@H](C)[C@H]12
InChI	InChI=1S/C22H31N3O6S2/c1-11-15-14(12(2)26)18(27)25(15)16(19(28)30-10-31-20(29)22(3,4)5)17(11)33-13-8-24(9-13)21-23-6-7-32-21/h11-15,26H,6-10H2,1-5H3/t11-,12-,14-,15-/m1/s1

Property Name	Value
Molecular Formula	C22H31N3O6S2
Molecular Weight	497.64
AlogP	1.67
Hydrogen Bond Acceptor	10.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	6.0
Polar Surface Area	108.74
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	33.0

Mechanism of Action	Action	Reference
Bacterial penicillin-binding protein inhibitor	INHIBITOR	PubMed PubMed

Resources	Reference
ChEBI	135799
ChEMBL	CHEMBL2107486
DrugCentral	2574
FDA SRS	95AK1A52I8
Guide to Pharmacology	10864
PubChem	9892071
SureChEMBL	SCHEMBL305541
ZINC	ZINC000004217736

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TEBIPENEM PIVOXIL

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Cross References