EcoDrugPlus


Synonyms	Mezlin Mezlocillin sodium Mezlocillin sodium monohydrate Mezlocillin sodium salt
Status
Molecule Category	Salt-form
UNII	RX227TP94U

Synonyms

Mezlin

Mezlocillin sodium

Mezlocillin sodium monohydrate

Mezlocillin sodium salt

Status

Molecule Category

Salt-form

UNII

RX227TP94U


InChI Key	GTGQRSIMEUWHPA-ZBJAFUORSA-M
Smiles	CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCN(S(C)(=O)=O)C3=O)c3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[Na+]
InChI	InChI=1S/C21H25N5O8S2.Na/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34;/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30);/q;+1/p-1/t12-,13-,14+,17-;/m1./s1

InChI Key

GTGQRSIMEUWHPA-ZBJAFUORSA-M

Smiles

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCN(S(C)(=O)=O)C3=O)c3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[Na+]

InChI

InChI=1S/C21H25N5O8S2.Na/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34;/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30);/q;+1/p-1/t12-,13-,14+,17-;/m1./s1

Property Name	Value
Molecular Formula	C21H24N5NaO8S2
Molecular Weight	561.57
AlogP	-0.23
Hydrogen Bond Acceptor	8.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	6.0
Polar Surface Area	173.5
Molecular species	ACID
Aromatic Rings	1.0
Heavy Atoms	36.0

Property Name

Value

Molecular Formula

C21H24N5NaO8S2

Molecular Weight

561.57

AlogP

-0.23

Hydrogen Bond Acceptor

8.0

Hydrogen Bond Donor

3.0

Number of Rotational Bond

6.0

Polar Surface Area

173.5

Molecular species

ACID

Aromatic Rings

1.0

Heavy Atoms

36.0

Mechanism of Action	Action	Reference
Bacterial penicillin-binding protein inhibitor	INHIBITOR	PubMed PubMed

Mechanism of Action

Action

Reference

Bacterial penicillin-binding protein inhibitor

INHIBITOR

PubMed PubMed

Resources	Reference
ChEBI	52067
ChEMBL	CHEMBL1697708
FDA SRS	RX227TP94U
PubChem	23685177
SureChEMBL	SCHEMBL41074

Resources

Reference

ChEBI

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

MEZLOCILLIN SODIUM

Structure

Physicochemical Descriptors

Pharmacology

Cross References