FLUORODOPA F 18


Synonyms	18f 18f-dopa 18f-l-fluoro-dopa Fdopa f-18 Fluorodopa (18f) Fluorodopa f 18 Fluorodopa f-18 Fluorodopa f18 L-6-(18f)fluoro-dopa
Status
Molecule Category	UNKNOWN
UNII	2C598205QX
EPA CompTox	DTXSID60239157


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	PAXWQORCRCBOCU-RPDRGXCHSA-N
Smiles	N[C@@H](Cc1cc(O)c(O)cc1[18F])C(=O)O
InChI	InChI=1S/C9H10FNO4/c10-5-3-8(13)7(12)2-4(5)1-6(11)9(14)15/h2-3,6,12-13H,1,11H2,(H,14,15)/t6-/m0/s1/i10-1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C9H10FNO4
Molecular Weight	214.18
AlogP	0.19
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	3.0
Polar Surface Area	103.78
Molecular species	ZWITTERION
Aromatic Rings	1.0
Heavy Atoms	15.0

Bioactivity

Mechanism of Action	Action	Reference
Diagnostic agent	None	DailyMed

Related Entries

Cross References

Resources	Reference
ChEBI	49166
ChEMBL	CHEMBL3400972
DrugBank	DB13848
DrugCentral	4550
FDA SRS	2C598205QX
SureChEMBL	SCHEMBL522323
ZINC	ZINC000100079068

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).