EcoDrugPlus


Synonyms	L-lysine-dextroamphetamine Lisdexamfetamine Lisdexamphetamine
Status
Molecule Category	Free-form
ATC	N06BA12
UNII	H645GUL8KJ
EPA CompTox	DTXSID00209652

Synonyms

L-lysine-dextroamphetamine

Lisdexamfetamine

Lisdexamphetamine

Status

Molecule Category

Free-form

ATC

N06BA12

UNII

H645GUL8KJ

EPA CompTox

DTXSID00209652


InChI Key	VOBHXZCDAVEXEY-JSGCOSHPSA-N
Smiles	C[C@@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN
InChI	InChI=1S/C15H25N3O/c1-12(11-13-7-3-2-4-8-13)18-15(19)14(17)9-5-6-10-16/h2-4,7-8,12,14H,5-6,9-11,16-17H2,1H3,(H,18,19)/t12-,14-/m0/s1

InChI Key

VOBHXZCDAVEXEY-JSGCOSHPSA-N

Smiles

C[C@@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN

InChI

InChI=1S/C15H25N3O/c1-12(11-13-7-3-2-4-8-13)18-15(19)14(17)9-5-6-10-16/h2-4,7-8,12,14H,5-6,9-11,16-17H2,1H3,(H,18,19)/t12-,14-/m0/s1

Property Name	Value
Molecular Formula	C15H25N3O
Molecular Weight	263.38
AlogP	1.19
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	8.0
Polar Surface Area	81.14
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	19.0

Property Name

Value

Molecular Formula

C15H25N3O

Molecular Weight

263.38

AlogP

1.19

Hydrogen Bond Acceptor

3.0

Hydrogen Bond Donor

3.0

Number of Rotational Bond

8.0

Polar Surface Area

81.14

Molecular species

BASE

Aromatic Rings

1.0

Heavy Atoms

19.0

Resources	Reference
ChEBI	135925
ChEMBL	CHEMBL1201222
DrugBank	DB01255
DrugCentral	4135
FDA SRS	H645GUL8KJ
Human Metabolome Database	HMDB0015385
Guide to Pharmacology	7213
PubChem	11597698
SureChEMBL	SCHEMBL158949
ZINC	ZINC000011680943

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Human Metabolome Database

HMDB0015385

Guide to Pharmacology

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

LISDEXAMFETAMINE

Structure

Physicochemical Descriptors

Cross References