EcoDrugPlus


Synonyms	NS 2330 NS-2330 Tesofensine
Status
Molecule Category	Free-form
UNII	BLH9UKX9V1


InChI Key	VCVWXKKWDOJNIT-ZOMKSWQUSA-N
Smiles	CCOC[C@@H]1[C@@H](c2ccc(Cl)c(Cl)c2)C[C@@H]2CC[C@H]1N2C
InChI	InChI=1S/C17H23Cl2NO/c1-3-21-10-14-13(9-12-5-7-17(14)20(12)2)11-4-6-15(18)16(19)8-11/h4,6,8,12-14,17H,3,5,7,9-10H2,1-2H3/t12-,13+,14+,17+/m0/s1

Property Name	Value
Molecular Formula	C17H23Cl2NO
Molecular Weight	328.28
AlogP	4.6
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	4.0
Polar Surface Area	12.47
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	21.0

Mechanism of Action	Action	Reference
Monoamine transporter inhibitor	INHIBITOR	PubMed PubMed PubMed

Resources	Reference
ChEMBL	CHEMBL3989690
DrugBank	DB06156
FDA SRS	BLH9UKX9V1
PubChem	11370864
SureChEMBL	SCHEMBL37509
ZINC	ZINC000003953158

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TESOFENSINE

Structure

Physicochemical Descriptors

Pharmacology

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