INDACATEROL


Synonyms	Indacaterol Indacterol Onbrez QAB-149 QAB149 QABI49
Status
Molecule Category	Free-form
ATC	R03AC18
UNII	8OR09251MQ
EPA CompTox	DTXSID90185198


InChI Key	QZZUEBNBZAPZLX-QFIPXVFZSA-N
Smiles	CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2
InChI	InChI=1S/C24H28N2O3/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29)/t22-/m0/s1

Property Name	Value
Molecular Formula	C24H28N2O3
Molecular Weight	392.5
AlogP	3.15
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	6.0
Polar Surface Area	85.35
Molecular species	BASE
Aromatic Rings	3.0
Heavy Atoms	29.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor	0.79-15.85	7.9-316.23	-	20.6-91.4	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	-	7.9-7.9	-	-	-
Homo sapiens	0.79-15.85	-	-	20.6-91.4	-

Header

Compound Name

Maximum Phase

Compound Structure

Smile

Inchi

InchiKey

Compound Properties

Molecular Formula

Molecular Weight

ALogP

PSA

Resources	Reference
ChEBI	68575
ChEMBL	CHEMBL1095777
DrugBank	DB05039
DrugCentral	4183
FDA SRS	8OR09251MQ
Human Metabolome Database	HMDB0015608
Guide to Pharmacology	7455
PharmGKB	PA165958348
PubChem	6918554
SureChEMBL	SCHEMBL48098
ZINC	ZINC000035801098

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

INDACATEROL

Structure

Physicochemical Descriptors

Pharmacology

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