EcoDrugPlus


Synonyms	(18f)facbc (18f)ge-148 Axumin FACBC Facbc f-18 Fluciclovine (18f) Fluciclovine f 18 Fluciclovine f-18 Fluciclovine f18 GE-148 GE-148 (18F) GE-148 F-18 NMK-36 NMK36
Status
Molecule Category	UNKNOWN
UNII	38R1Q0L1ZE

Synonyms

(18f)facbc

(18f)ge-148

Axumin

FACBC

Facbc f-18

Fluciclovine (18f)

Fluciclovine f 18

Fluciclovine f-18

Fluciclovine f18

GE-148

GE-148 (18F)

GE-148 F-18

NMK-36

NMK36

Status

Molecule Category

UNKNOWN

UNII

38R1Q0L1ZE


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70


InChI Key	NTEDWGYJNHZKQW-DGMDOPGDSA-N
Smiles	N[C@]1(C(=O)O)C[C@@H]([18F])C1
InChI	InChI=1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/t3-,5-/i6-1

InChI Key

NTEDWGYJNHZKQW-DGMDOPGDSA-N

Smiles

N[C@]1(C(=O)O)C[C@@H]([18F])C1

InChI

InChI=1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/t3-,5-/i6-1

Property Name	Value
Molecular Formula	C6H10FNO2
Molecular Weight	146.15
AlogP	0.29
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	1.0
Polar Surface Area	63.32
Molecular species	ZWITTERION
Aromatic Rings	0.0
Heavy Atoms	10.0

Property Name

Value

Molecular Formula

C6H10FNO2

Molecular Weight

146.15

AlogP

0.29

Hydrogen Bond Acceptor

2.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

1.0

Polar Surface Area

63.32

Molecular species

ZWITTERION

Aromatic Rings

0.0

Heavy Atoms

10.0

Mechanism of Action	Action	Reference
Diagnostic agent	None	DailyMed

Mechanism of Action

Action

Reference

Diagnostic agent

None

DailyMed

Resources	Reference
ChEMBL	CHEMBL3707267
FDA SRS	38R1Q0L1ZE

Resources

Reference

ChEMBL

CHEMBL3707267

FDA SRS

38R1Q0L1ZE


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

FLUCICLOVINE F18

Structure

Physicochemical Descriptors

Bioactivity

Cross References