EcoDrugPlus


Synonyms	A-4828 NSC-109723 Trofosfamide Trophosphamide Z-4828
Status
Molecule Category	Free-form
ATC	L01AA07
UNII	H64JRU6GJ0


InChI Key	UMKFEPPTGMDVMI-UHFFFAOYSA-N
Smiles	O=P1(N(CCCl)CCCl)OCCCN1CCCl
InChI	InChI=1S/C9H18Cl3N2O2P/c10-2-6-13-5-1-9-16-17(13,15)14(7-3-11)8-4-12/h1-9H2

Property Name	Value
Molecular Formula	C9H18Cl3N2O2P
Molecular Weight	323.59
AlogP	2.84
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	7.0
Polar Surface Area	32.78
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	17.0

Resources	Reference
ChEBI	135381
ChEMBL	CHEMBL462019
DrugBank	DB12902
DrugCentral	2766
FDA SRS	H64JRU6GJ0
PubChem	65702
SureChEMBL	SCHEMBL8236

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TROFOSFAMIDE

Structure

Physicochemical Descriptors

Related Entries

Cross References