TEZACITABINE

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Synonyms
Status
Molecule Category Mixture
UNII 7607Y95N9S
EPA CompTox DTXSID10156446

Structure

InChI Key GFFXZLZWLOBBLO-ASKVSEFXSA-N
Smiles Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)/C2=C\F)c(=O)n1
InChI
InChI=1S/C10H12FN3O4/c11-3-5-8(16)6(4-15)18-9(5)14-2-1-7(12)13-10(14)17/h1-3,6,8-9,15-16H,4H2,(H2,12,13,17)/b5-3+/t6-,8+,9-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H12FN3O4
Molecular Weight 257.22
AlogP -1.07
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 2.0
Polar Surface Area 110.6
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 18.0

Pharmacology

Mechanism of Action Action Reference
Ribonucleoside-diphosphate reductase RR1 inhibitor INHIBITOR PubMed PubMed

Cross References

Resources Reference
ChEMBL CHEMBL2105467
DrugBank DB06433
FDA SRS 7607Y95N9S
PubChem 9925544
SureChEMBL SCHEMBL18724
ZINC ZINC000003777826
ChEMBL CHEMBL3989496
FDA SRS UCC4EQS7WL
PubChem 9925544
SureChEMBL SCHEMBL8294060
CONTENTS