TALAMPANEL

/static/temp/default.svg Search structure
Synonyms
Status
Molecule Category Free-form
UNII CVS43XG1L5
EPA CompTox DTXSID10167259

Structure

InChI Key JACAAXNEHGBPOQ-LLVKDONJSA-N
Smiles CC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2C[C@H]1C)OCO3
InChI
InChI=1S/C19H19N3O3/c1-11-7-14-8-17-18(25-10-24-17)9-16(14)19(21-22(11)12(2)23)13-3-5-15(20)6-4-13/h3-6,8-9,11H,7,10,20H2,1-2H3/t11-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H19N3O3
Molecular Weight 337.38
AlogP 2.54
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 77.15
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 25.0

Pharmacology

Mechanism of Action Action Reference
Glutamate receptor ionotropic, AMPA 1 antagonist ANTAGONIST PubMed

Target Conservation

Protein: Glutamate receptor ionotropic, AMPA 1
Description: Glutamate receptor 1
Organism : Homo sapiens
P42261 ENSG00000155511
Protein: Glutamate receptor ionotropic, AMPA 2
Description: Glutamate receptor 2
Organism : Homo sapiens
P42262 ENSG00000120251

Cross References

Resources Reference
ChEBI 34992
ChEMBL CHEMBL61872
DrugBank DB04982
FDA SRS CVS43XG1L5
Guide to Pharmacology 8279
KEGG C13670
PubChem 164509
SureChEMBL SCHEMBL118011
ZINC ZINC000003823565
CONTENTS