SAROGLITAZAR

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Synonyms
Status
Molecule Category Free-form
UNII E0YMX3S4JD
EPA CompTox DTXSID10197819

Structure

InChI Key MRWFZSLZNUJVQW-DEOSSOPVSA-N
Smiles CCO[C@@H](Cc1ccc(OCCn2c(C)ccc2-c2ccc(SC)cc2)cc1)C(=O)O
InChI
InChI=1S/C25H29NO4S/c1-4-29-24(25(27)28)17-19-6-10-21(11-7-19)30-16-15-26-18(2)5-14-23(26)20-8-12-22(31-3)13-9-20/h5-14,24H,4,15-17H2,1-3H3,(H,27,28)/t24-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H29NO4S
Molecular Weight 439.58
AlogP 5.3
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 11.0
Polar Surface Area 60.69
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 31.0

Pharmacology

Mechanism of Action Action Reference
Peroxisome proliferator-activated receptor alpha agonist AGONIST PubMed PubMed PubMed

Target Conservation

Protein: Peroxisome proliferator-activated receptor gamma
Description: Peroxisome proliferator-activated receptor gamma
Organism : Homo sapiens
P37231 ENSG00000132170
Protein: Peroxisome proliferator-activated receptor alpha
Description: Peroxisome proliferator-activated receptor alpha
Organism : Homo sapiens
Q07869 ENSG00000186951

Cross References

Resources Reference
ChEBI 134708
ChEMBL CHEMBL4297530
DrugBank DB13115
DrugCentral 5047
FDA SRS E0YMX3S4JD
PDB EWR
PubChem 60151560
SureChEMBL SCHEMBL16346340
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