EcoDrugPlus


Synonyms	Ropivacaine Ropivicaine TLC-590 TLC590 Tlc590
Status
Molecule Category	Free-form
ATC	N01BB09
UNII	7IO5LYA57N
EPA CompTox	DTXSID4040187


InChI Key	ZKMNUMMKYBVTFN-HNNXBMFYSA-N
Smiles	CCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C
InChI	InChI=1S/C17H26N2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1

Property Name	Value
Molecular Formula	C17H26N2O
Molecular Weight	274.41
AlogP	3.51
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	4.0
Polar Surface Area	32.34
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	20.0

Resources	Reference
ChEBI	8890
ChEMBL	CHEMBL1077896
DrugBank	DB00296
DrugCentral	2403
FDA SRS	7IO5LYA57N
Human Metabolome Database	HMDB0014441
Guide to Pharmacology	7602
KEGG	C07532
PubChem	175805
SureChEMBL	SCHEMBL33292
ZINC	ZINC000000897002

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

ROPIVACAINE

Structure

Physicochemical Descriptors

Related Entries

Cross References