POLIHEXANIDE


Synonyms	Cosmocil cq Lavasept Microcare mbg Polihexanide Polihexanide hydrochloride Poly(hexamethylenebiguanide) Polyhexamethylene biguanide Polyhexanide Purista Vantocil
Status
Molecule Category	UNKNOWN
ATC	D08AC05
UNII	322U039GMF
EPA CompTox	DTXSID40873856


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	VAZJLPXFVQHDFB-UHFFFAOYSA-N
Smiles	CCCCCCNC(=N)NC(=N)N
InChI	InChI=1S/C8H19N5/c1-2-3-4-5-6-12-8(11)13-7(9)10/h2-6H2,1H3,(H6,9,10,11,12,13)

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C8H19N5
Molecular Weight	185.27
AlogP	0.57
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	5.0
Number of Rotational Bond	5.0
Polar Surface Area	97.78
Molecular species	BASE
Aromatic Rings	0.0
Heavy Atoms	13.0

Related Entries

Cross References

Resources	Reference
ChEMBL	CHEMBL2106939
FDA SRS	322U039GMF
SureChEMBL	SCHEMBL45011
ZINC	ZINC000004217340

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).