EcoDrugPlus


Synonyms	DRM-01B DRM01B DRMO1B Olumacostat glasaretil
Status
Molecule Category	Free-form
UNII	4W6JDK2PLY

Synonyms

DRM-01B

DRM01B

DRMO1B

Olumacostat glasaretil

Status

Molecule Category

Free-form

UNII

4W6JDK2PLY


InChI Key	FYJLDICZGDFWKP-UHFFFAOYSA-N
Smiles	CCCCCCCCCCCCCCOc1ccc(C(=O)OCC(=O)N(C)CC(=O)OCC)o1
InChI	InChI=1S/C26H43NO7/c1-4-6-7-8-9-10-11-12-13-14-15-16-19-32-25-18-17-22(34-25)26(30)33-21-23(28)27(3)20-24(29)31-5-2/h17-18H,4-16,19-21H2,1-3H3

InChI Key

FYJLDICZGDFWKP-UHFFFAOYSA-N

Smiles

CCCCCCCCCCCCCCOc1ccc(C(=O)OCC(=O)N(C)CC(=O)OCC)o1

InChI

InChI=1S/C26H43NO7/c1-4-6-7-8-9-10-11-12-13-14-15-16-19-32-25-18-17-22(34-25)26(30)33-21-23(28)27(3)20-24(29)31-5-2/h17-18H,4-16,19-21H2,1-3H3

Property Name	Value
Molecular Formula	C26H43NO7
Molecular Weight	481.63
AlogP	5.54
Hydrogen Bond Acceptor	7.0
Number of Rotational Bond	20.0
Polar Surface Area	95.28
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	34.0

Property Name

Value

Molecular Formula

C26H43NO7

Molecular Weight

481.63

AlogP

5.54

Hydrogen Bond Acceptor

7.0

Number of Rotational Bond

20.0

Polar Surface Area

95.28

Molecular species

NEUTRAL

Aromatic Rings

1.0

Heavy Atoms

34.0

Mechanism of Action	Action	Reference
Acetyl-CoA carboxylase inhibitor	INHIBITOR	PubMed Other

Mechanism of Action

Action

Reference

Acetyl-CoA carboxylase inhibitor

INHIBITOR

PubMed Other

Resources	Reference
ChEMBL	CHEMBL3989947
DrugBank	DB12642
FDA SRS	4W6JDK2PLY
PubChem	89497391
SureChEMBL	SCHEMBL14856848

Resources

Reference

ChEMBL

DrugBank

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

OLUMACOSTAT GLASARETIL

Structure

Physicochemical Descriptors

Pharmacology

Cross References