EcoDrugPlus


Synonyms	Nemonoxacin TG-873870
Status
Molecule Category	Free-form
ATC	J01MB08
UNII	P94L0PVO94


InChI Key	AVPQPGFLVZTJOR-RYUDHWBXSA-N
Smiles	COc1c(N2C[C@@H](C)C[C@H](N)C2)ccc2c(=O)c(C(=O)O)cn(C3CC3)c12
InChI	InChI=1S/C20H25N3O4/c1-11-7-12(21)9-22(8-11)16-6-5-14-17(19(16)27-2)23(13-3-4-13)10-15(18(14)24)20(25)26/h5-6,10-13H,3-4,7-9,21H2,1-2H3,(H,25,26)/t11-,12-/m0/s1

Property Name	Value
Molecular Formula	C20H25N3O4
Molecular Weight	371.44
AlogP	2.22
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	4.0
Polar Surface Area	97.79
Molecular species	ZWITTERION
Aromatic Rings	2.0
Heavy Atoms	27.0

Mechanism of Action	Action	Reference
Bacterial DNA gyrase inhibitor	INHIBITOR	PubMed Other PubMed

Resources	Reference
ChEBI	136053
ChEMBL	CHEMBL1213456
DrugBank	DB06600
DrugCentral	5079
FDA SRS	P94L0PVO94
Guide to Pharmacology	10836
PubChem	11993740
SureChEMBL	SCHEMBL1006373
ZINC	ZINC000040435195

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

NEMONOXACIN

Structure

Physicochemical Descriptors

Pharmacology

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