EcoDrugPlus


Synonyms	4-methylephedrone 4-methylmethcathinone 4-mmc J2.756.280I M-cat Meow meow Mephedrone
Status
Molecule Category	Free-form
UNII	8BA8T27317
EPA CompTox	DTXSID20891437


InChI Key	YELGFTGWJGBAQU-UHFFFAOYSA-N
Smiles	CNC(C)C(=O)c1ccc(C)cc1
InChI	InChI=1S/C11H15NO/c1-8-4-6-10(7-5-8)11(13)9(2)12-3/h4-7,9,12H,1-3H3

Property Name	Value
Molecular Formula	C11H15NO
Molecular Weight	177.25
AlogP	1.79
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	3.0
Polar Surface Area	29.1
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	13.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family	49.1-118	-	-	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	49.1-118	-	-	-	-

Resources	Reference
CAS NUMBER	1189805-46-6
ChEBI	59331
ChEMBL	CHEMBL4094396
DrugBank	DB13108
FDA SRS	8BA8T27317
Human Metabolome Database	HMDB0041923
PubChem	45266826
SureChEMBL	SCHEMBL727913

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

MEPHEDRONE

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Pharmacology

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