LEUCINE

/static/temp/default.svg Search structure
Synonyms
Status
Molecule Category Free-form
UNII GMW67QNF9C
EPA CompTox DTXSID9023203

Structure

InChI Key ROHFNLRQFUQHCH-YFKPBYRVSA-N
Smiles CC(C)C[C@H](N)C(=O)O
InChI
InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H13NO2
Molecular Weight 131.18
AlogP 0.44
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 3.0
Polar Surface Area 63.32
Molecular species ZWITTERION
Aromatic Rings 0.0
Heavy Atoms 9.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC03 and SLC07 families of heteromeric amino acid transporters (HATs) SLC07 Cationic amino acid transporter/glycoprotein-associated family
- - - - 73-78
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Aquifex aeolicus
- - 20 - -
Homo sapiens
- - - - 73-78

Cross References

Resources Reference
ChEBI 57427
ChEMBL CHEMBL291962
DrugBank DB00149
DrugCentral 1557
FDA SRS GMW67QNF9C
Human Metabolome Database HMDB0062203
Guide to Pharmacology 3312
KEGG C00123
PDB LEU
PubChem 6106
SureChEMBL SCHEMBL3889
ZINC ZINC000003645145
CONTENTS