EcoDrugPlus


Synonyms	Glycopyrrolate cation Glycopyrrolate ion Glycopyrronium Glycopyrronium cation Glycopyrronium ion Glycopyrronium, erythro-
Status
Molecule Category	Free-form
ATC	D11AA01
UNII	A14FB57V1D
EPA CompTox	DTXSID2048165


InChI Key	ANGKOCUUWGHLCE-UHFFFAOYSA-N
Smiles	C[N+]1(C)CCC(OC(=O)C(O)(c2ccccc2)C2CCCC2)C1
InChI	InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1

Property Name	Value
Molecular Formula	C19H28NO3+
Molecular Weight	318.44
AlogP	2.46
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	4.0
Polar Surface Area	46.53
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	23.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Acetylcholine receptor	-	0.1259-0.2512	-	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	-	-	0.5012	-	-
Homo sapiens	-	0.1259-0.2512	-	-	-

Resources	Reference
ChEBI	94449
ChEMBL	CHEMBL1201335
DrugBank	DB00986
DrugCentral	4302
FDA SRS	A14FB57V1D
Human Metabolome Database	HMDB0015121
Guide to Pharmacology	7459
PharmGKB	PA164754882
PubChem	9933193
SureChEMBL	SCHEMBL133002

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

GLYCOPYRRONIUM

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