FOSINOPRIL

/static/temp/default.svg Search structure
Synonyms
Status
Molecule Category Free-form
ATC C09AA09
UNII R43D2573WO

Structure

InChI Key BIDNLKIUORFRQP-XYGFDPSESA-N
Smiles CCC(=O)O[C@@H](O[P@](=O)(CCCCc1ccccc1)CC(=O)N1C[C@H](C2CCCCC2)C[C@H]1C(=O)O)C(C)C
InChI
InChI=1S/C30H46NO7P/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)/t25-,26+,30+,39-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C30H46NO7P
Molecular Weight 563.67
AlogP 6.12
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 14.0
Polar Surface Area 110.21
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 39.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Protease Metallo protease Metallo protease MAE clan Metallo protease M2 family
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Cross References

Resources Reference
ChEMBL CHEMBL3039598
DrugCentral 1245
FDA SRS R43D2573WO
Guide to Pharmacology 6456
PubChem 45357796
SureChEMBL SCHEMBL5928355
ZINC ZINC000003977764
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