None is not found in the database.

FENFLURAMINE HYDROCHLORIDE

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Search structure


Synonyms	AHR-3002 Dl-fenfluramine hydrochloride Fenfluramine hcl Fenfluramine hydrochloride Fintepla Ganal HHR-965 Ponderax Ponderax pacaps Pondimin
Status
Molecule Category	Salt-form
UNII	3KC089243P
Parent Compound:	FENFLURAMINE

Structure


InChI Key	ZXKXJHAOUFHNAS-UHFFFAOYSA-N
Smiles	CCNC(C)Cc1cccc(C(F)(F)F)c1.Cl
InChI	InChI=1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C12H17ClF3N
Molecular Weight	267.72
AlogP	3.25
Hydrogen Bond Acceptor	1.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	4.0
Polar Surface Area	12.03
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	16.0

Pharmacology

Mechanism of Action	Action	Reference
Serotonin 1d (5-HT1d) receptor agonist	AGONIST	PubMed PubMed PubMed PubMed

Target Conservation


Protein: Serotonin 1d (5-HT1d) receptor Description: 5-hydroxytryptamine receptor 1D Organism : Homo sapiens P28221 ENSG00000179546








Protein: Serotonin 2c (5-HT2c) receptor Description: 5-hydroxytryptamine receptor 2C Organism : Homo sapiens P28335 ENSG00000147246












Protein: Sigma opioid receptor Description: Sigma non-opioid intracellular receptor 1 Organism : Homo sapiens Q99720 ENSG00000147955

Cross References

Resources	Reference
ChEBI	59729
ChEMBL	CHEMBL2106217
FDA SRS	3KC089243P
PubChem	91452
SureChEMBL	SCHEMBL39491

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025