EPHEDRINE


Synonyms	(-)-ephedrine Ephedrine Ephedrine, anhydrous Ephedrinum, anhydrous L-ephedrine NSC-170951 NSC-8971 Xenadrine
Status
Molecule Category	Free-form
ATC	C01CA26 R01AA03 R01AB05 S01FB02
UNII	GN83C131XS
EPA CompTox	DTXSID0022985


InChI Key	KWGRBVOPPLSCSI-WPRPVWTQSA-N
Smiles	CN[C@@H](C)[C@H](O)c1ccccc1
InChI	InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m0/s1

Property Name	Value
Molecular Formula	C10H15NO
Molecular Weight	165.24
AlogP	1.33
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	3.0
Polar Surface Area	32.26
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	12.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Phosphatase	-	-	-	-	0
Enzyme	-	-	-	-	0

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	-	-	0-0

Header

Compound Name

Maximum Phase

Compound Structure

Smile

Inchi

InchiKey

Compound Properties

Molecular Formula

Molecular Weight

ALogP

PSA

Countries
Croatia
Czech Republic
Germany
Hungary
Romania
Serbia
Slovenia

Resources	Reference
ChEBI	15407
ChEMBL	CHEMBL211456
DrugBank	DB01364
DrugCentral	1024
FDA SRS	GN83C131XS
Human Metabolome Database	HMDB0015451
Guide to Pharmacology	556
KEGG	C01575
PharmGKB	PA449466
PubChem	9294
SureChEMBL	SCHEMBL4785
ZINC	ZINC000000074836

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

EPHEDRINE

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Environmental Exposure

Cross References